Eligibility criteria:

• Horses ≥ 12 months of age

• Horses with a suspicion of non-ocular Squamous Cell Carcinoma (Diagnosis will be confirmed prior to study treatment)

• Horses with chronic disease that is well controlled and life expectancy >6 months

• Horse owner must be willing to comply with all scheduled study visits

Exclusion criteria:

• Concurrent diagnosis of malignant cancer other than squamous cell carcinoma with an expected survival <6 months

• Previous treatment with radiation therapy or immunotherapy

• Pregnant or lactating

Other inclusion/exclusion criteria not listed will be discussed with you, including medications that are not allowed.

Study details:

Your horse will be screened to confirm that they can be included in the study. During screening the study site will obtain a medical history, physical examination, measurements and photos of your horse’s mass(es), blood and urine, and tissue samples from the mass(es). These procedures may be repeated throughout the study. This is an open label, non-randomized, prospective clinical trial and all horses will receive the study treatment.

Owner benefit:

This is a fully funded clinical trial. All study tests, study procedures, and study treatment is no cost to you. If your horse has a reaction to the study treatment, the Sponsor will cover the costs relating to the study treatment up to $750. Any costs above $750, the Sponsor will work with the study veterinarian to cover reasonable expenses relating to side effects from the study treatment. If your horse is excluded or removed from the study, you can pursue further care for your horse with no penalty (future examinations and procedures will not be covered by the study).